Genetic Recombination - Understanding the Mechanism

Molecular mechanism for genetic recombination.

Symmetry considerations of proteinnucleic acid interaction suggest the existence of an alternate branched configuration for DNA induced by binding specific structural proteins to symmetrically arranged polynucleotide base sequences. The concept that such sequences exist at the ends of genes or operons leads to a molecular model for genetic recombination in eukaryotic cells.

The Mechanism of Genetic Recombination in Phage.

Understanding the Mechanism Underlie the Antidiabetic Activity of Oleuropein Using Ex-Vivo Approach

Background: Oleuropein, the main constituent of olive fruit and leaves, has been reported to protect against insulin resistance and diabetes. While many experimental investigations have examined the mechanisms by which oleuropein improves insulin resistance and diabetes, much of these investigations have been carried out in either muscle cell lines or in vivo models two scenarios with many draw...

Understanding the Biases of Generalised Recombination

In this paper we propose, model theoretically and study a general notion of recombination for fixed-length strings where homologous recombination, inversion, gene duplication, gene deletion, diploidy and more are just special cases. The analysis of the model reveals that the notion of schema emerges naturally from the model’s equations. The study provides a variety of fixed points for the case ...

Modification for the Mechanism of Retroviral Recombination

Figure 1: The original minus strand exchange model. (A) The retroviral virion contains two essentially identical RNA molecules. (B) An extended singlestranded DNA molecule is left tailing behind. This single-stranded DNA tail is free to form a hybrid duplex with another RNA molecule. (C) The original template will be displaced by branch migration of the second RNA. This second RNA molecule will...